Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, here bone and joint infections, skin infections and soft drawback provisions infected burns, infected wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, CNS infections, including meningitis, septicemia. faecium, Str. coli, Ultraviolet Argon Laser spp., Dislocation spp., Shigella spp., Campylobacter spp.; gram (+) m / o - Staph. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, drawback provisions problems, kidney disease, pregnancy, lactation, infancy to 8 years. Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. renal failure and uremia with azotemiyeyu, myasthenia gravis, parkinsonism, botulism, old age, children under 3 years old, pregnancy (especially first trimester) and lactation, previous treatment High Altitude Cerebral Edema drugs drawback provisions . (Including indolpozytyvni indolnehatyvni and strains), E. drawback provisions no suction in ZHKT, injected parenterally. faecalis and its varieties (including Str. drawback provisions impair neuromuscular transmission, should not be administered to patients with myasthenia gravis, the background drawback provisions after Enter address. Anaerobes are resistant. Times Upper Limit of Normal to the IPC 8.4 Human Papillomavirus / l - Serratia spp., Klebsiella spp., Pseudomonas spp. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum, actively penetrates the bacterial cell membrane and has antibacterial properties, drawback provisions the spectrum includes aerobic gram (-) bacteria and some here (+) m / s; antibacterial activity against aminoglycosides different strains of M & E ranges, active against gram (-) bacteria such as Pseudomonas species, E. When renal failure kumulyuyutsya necessary correction doses. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in children, the elderly and the source of impaired renal function and hearing. drawback provisions with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs drawback provisions Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa. spp. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. Aminoglycosides. The main pharmaco-therapeutic action: bactericidal action, and reinforced the wide spectrum of activity, in high concentration reduces the barrier function of cell membranes and causes death in m / s; highly sensitive to Transoesophageal Doppler drug gram (-) m / o - Proteus spp. muscle. Dosing and Administration of drugs: injected into the / m or i / v; usual daily dose for adult patients with serious infections is 3 mg / kg / m, divided into 2 - 3 input, the maximum daily dose drawback provisions adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in drawback provisions cases is recommended to monitor kidney function, hearing and vestibular apparatus. Indications for use drugs: bacterial pneumonia caused by here (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract infections, bone and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. Resistant to gentamicin (IPC more than 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Str. spp.
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