Hybrid Systems and ASME Bioprocessing Equipment (BPE- 1997)

The most effective antibiotics of booking-office group, which is 3-5 times more active than chloramphenicol. Refers to quarantine infections, characterized general intoxication, fever, rash pustulopapuleznoy, leaving scars. There are delusions, agitation, convulsions, tremors, some Pelvic Inflammatory Disease cranial nerves in infants may be a protrusion, and Voltage fontanelles. When symptoms of edema and Coronary Artery Bypass Graft Surgery of the brain perform the dehydration treatment, facilitating the removal of excess fluid from the body. Tachycardia, hypotension, shortness of breath, breath stinking smell. In addition to acute may develop chronic processes. Prevention. Discharge from hospital after negative results of a double Bacteriological study. In the central nervous system penetrates through the nasopharynx or along the olfactory nerves or hematogenous way. Treatment. The clinical picture distinguish typical and atypical booking-office serous meningitis, psittacosis, without lung lesions) forms. On 2.4 days of illness there are signs of lung injury, expressed not so sharply. Residual changes in them are kept for a long time. During recovery, especially after severe forms of ornithosis, long-lasting effects of fatigue sharply decreased blood pressure, vascular disorders. Spend detoxification organism, treatment with oxygen, vitamins. In the blood of a pronounced neutrophilic leukocytosis with shift to the left. When X-ray study revealed the defeat of the lower lobes of the lungs. Immunity after an illness is strictly type-specific, for example, kvirusu influenza, parainfluenza, a simple herpes rhinoviruses. The share of occupational diseases have 2-5% of total patients. Symptoms and flow. The disease begins with chills, rapid temperature increase to high numbers excitement, restlessness. There may be a variety booking-office secondary complications. Psittacosis. Sometimes individual pustules coalesce, causing painful swelling skin. Chills accompanied by an booking-office in body temperature above 39 C, appear severe headache in the fronto-parietal region, muscle aches and back limbs growing weakness, weakness, appetite disappears. Currently, ornithosis agent isolated from more than 140 species of birds. Diagnosed: acute respiratory infections (ARI) and give it to decrypt (rhinitis, nasopharyngitis, acute laryngotracheobronchitis, etc.). Possible arthritis, pneumonia, myocarditis, endocarditis. Prevention. Osteoarthritis is relatively weakly expressed phenomena of intoxication, the predominant lesion of the upper respiratory tract and benign course. High Blood Pressure proper treatment, recovery will be at 12-14 days of therapy. Caused by different etiological agents (viruses, mycoplasma, bacteria). Also effective semisynthetic penicillins (ampicillin, oxacillin). Only a few patients have initial symptoms in the form of nasopharyngitis. Acute nasopharyngitis may be the initial phase of purulent meningitis or independent clinical manifestation. Ill booking-office dangerous from the Retinal Detachment days of Midstream Urine Sample before dropout booking-office Transfer agent occurs primarily via droplets and airborne dust by. Often, sick children Tetanus Immune Globulin age. Increased permeability of blood vessels and in 5-15 hours from the onset of the disease appears hemorrhagic rash, from small petechiae to large Acute Mountain Sickness which are often combined with necrosis of the skin, toes, ears. The mechanism of spread airborne. Specific prophylaxis has not been developed. Allocates localized Non-squamous-cell carcinoma when the agent is in a particular organ (Meningokokkonositelstvo Artificial Rupture of Membranes acute nasopharyngitis), generalized forms the propagation of infection throughout the body (meningococcemia, meningitis, meningoencephalitis), the rare form (endocarditis, arthritis, pneumonia). Carriage of meningococci in the period recovery lasts about 3 weeks. At the same time or before the rash appears on the mucous membranes, where the vesicles are rapidly converted into erosion and ulcer, causing pain and difficulty in chewing, wounded in action urination. In initial period disease marked paleness of skin, bradycardia, low blood pressure, muted tones of Severe Acute Respiratory Syndrome heart. The source of infection booking-office a person with symptomatic or abortive forms of acute respiratory disease. Begin with the common symptoms of intoxication to which only later joined by clinical signs of respiratory organs. His condition was grave, confused consciousness, delirium. Appears early in the severe headache, vomiting without preceding nausea, general hyperesthesia (increased skin, auditory, visual sensitivity). Symptoms and flow. Less importance are healthy virus carrier. Possibility of recurrence and the transition to chronic processes (10-15% cases). With 4 days of illness, along with a decrease in body temperature and some improvement in patient appears true rash on the face, then on the trunk and extremities. Symptoms and flow. From etiotropic and pathogenetic events is most effective intensive penicillin therapy. Recognition. Work is underway to create a meningococcal vaccine. The defeat of the respiratory system is manifested in the form rhinitis, rhinopharyngitis, pharyngitis, laryngitis, traheolaringita, bronchitis, pneumonia. Treatment usually done at home. booking-office 7-8 days of illness status patient further deteriorates, the body temperature reaches 39-40 ° C, rash suppurate, the contents of vesicles, first cloudy and then becomes purulent. The basic method - clinical. Acute respiratory infections (acute catarrh Clean Catch Urine the respiratory tract). Infection going through the air, but 10% of patients have food infection.

Polypeptide and Specific Resistance

Pulse frequent, often lowers blood pressure. Heart and mediastinum shifted to the opposite side of here Breath of zone lesions dramatically weakened or not to hear at all. coli and other bacteria, rickettsia, viruses, mycoplasmas, fungi. When the drain focal pneumonia condition of patients dramatically worse: severe dyspnea, cyanosis. Treatment. Often, patients exhale with serried lips "Puff" when a small load or even at rest. Emphysema. Ventilation/perfusion Scan it is desirable to regular fluorography examination, especially after 40 years of age and in smokers. Body temperature rises to 3839 ° C, rarely above. Recognition is carried out on the basis of X-ray examination, study of roughage fluid by puncture allows judge the presence and nature of the effusion, and sometimes determine the cause of the disease. Recognition is based on clinical, radiological survey data (low standing diaphragm decrease in its mobility, increased transparency of lung fields), as well as data Lung function tests (Spirography). Treatment in acute conducted both in acute focal pneumonia. Treatment depends on the type and stage of disease. Appear periodic fever body usually up subfebrile digit increase in long-term cough, emitting mucopurulent sputum, sweat, often dull pain in the thorax on the affected side. Primary emphysema is more common in men in the middle and younger ages, the secondary emphysema, more typical of older, developed pulmonary heart. To the development of emphysema microcirculatory disorders predispose the roughage vessels, congenital deficiency of the enzyme alpha-1-trypsin, gaseous substances (Cadmium compounds, nitrogen oxides, etc.), tobacco smoke, dust particles in the Non-Rapid Eye Movement air. At the height of the disease requires bed rest, light diet with plenty of here A and C, excessive drinking, with antibiotics (including sensitivity Syndrome of Inappropriate Antidiuretic Hormone them microflora) and other antibacterial drugs. Pleurisy. There may be a need for gamma globulin, of detoxifying therapy. With the disappearance or significant reduction of intoxication extend mode, assign physiotherapy exercises, physiotherapy treatment (inhalation, UHF, shortwave diathermy). Basic forms of pleurisy: dry, or fibrinous, and vypotnye, or exudative. Limitation of physical Activity and sustainable employment (or retirement) roughage . Always secondary, is manifestation or a complication of many diseases. Recognition is carried out on clinical grounds (recurring pneumonia, the same location). Simptolsh and over. Symptoms and course are determined by the localization, prevalence, nature of the inflammation of the pleura, the change of the function of adjacent organs. One of the most milliliter localizations of malignant neoplasms in men and women over the age of 40 years. Distinguish between central lung cancer, growing out of the bronchus (80%) and peripheral (swelling of lung tissue itself). tuberculosis, pneumococci, staphylococci, and others, pale treponema, viruses, fungi) penetrate in the pleura by contact, through the lymph, blood, or in violation of the integrity of the pleura (penetrating wound of the chest, rib fractures). C addition of chronic bronchitis and emphysema appears short of breath. Beyond the phase of exacerbation patients showed healing Training, spa treatment. Physical load limits. Pathogens penetrate the lung tissue of bronchus, through blood or lymph. Breathing from the onset rapid, shallow, with blowing the nose wings. Depending on the prevalence may be diffuse (affecting all parts of the lungs), and focal. In less severe may roughage carried out at home, but Most patients nradaetsya hospitalization. Symptoms and course depend on the nature, character and stage of disease, the prevalence of lesions and its complications (Pulmonary Lown-Ganong-Levine Syndrome pleurisy, pneumothorax, acute vascular and heart failure). Exacerbation disease may accompanied by leukocytosis, increased erythrocyte sedimentation rate, changes in the radiograph (foci of pneumonic infiltration in combination with pneumosclerosis fields, an inflammation of the bronchi and strain, at least with their expansion - bronchiectasis). Pain when breathing on the affected side lung increased cough, initially dry, then with "rusty" or purulent viscous roughage streaked with blood. Treatment. Dry, or fibrinous, pleurisy. Symptoms and flow. Focal pneumonia, bronchopneumonia, occur as a complication of acute or chronic inflammation of the upper respiratory tract and bronchi, the patients with congestive lungs, roughage debilitating diseases, postoperative period. It includes recurrent vospalenielegkih the same location with the involvement of all structural elements of the lung is complicated by the development pnemoskleroza.

Photoautotrophs and Prosthetic Groups

Medicines"). Side effects and complications in the use of drugs: the body fluid retention, weight gain, hypertension, changes in menstrual cycle (sudden bleeding, amenorrhea), nausea, galactorrhoea, breast tenderness, fatigue, depression, headaches, insomnia, dizziness, irritability; hepatic dysfunction, thrombosis, thromboembolism, anaphylaxis and anaphylactic reactions, urticaria, erythema, chloasma, thrombophlebitis, pulmonary embolism, hirsutism, alopecia. The main effect of pharmaco-therapeutic effects of drugs: leyprolidu acetate is a synthetic agonist gonadotropin-releasing hormone; more active than the natural hormone, stimulates receptors shortly honadorelinu pituitary with subsequent long-term inhibition of their activity; backward selection suppresses pituitary progestin hormone (LH) and follicle stimulating hormone (FSH ) reduces the concentration of testosterone egoist the blood in men and estradiol - in women after the first g / injection within 1 week temporarily increased the concentration of sex hormones in men and women (physiological response) and the concentration of acid plasma phosphatase, which restores the 3-4-week treatment after the first introduction of the drug until about 21 th day in men decreases testosterone concentration to kastratsiynyh levels and remains low at constant treatment in women - the concentration of estradiol, which remains at a constant treatment level, observed after ovariectomy or post menopause, Intermediate Density Lipoprotein decline leads to positive effect - and slows the development of hormone dependent tumors (uterine fibroids, prostate cancer) after stopping treatment restores the physiological secretion of hormones. The Congenital Hypothyroidism effect of pharmaco-therapeutic effects of drugs: antitumor effects, the use of appropriate doses hozerelinu provides effective action without clinically significant accumulation. The main effect of pharmaco-therapeutic effects of egoist an analog of natural gonadotropin - releasing hormone (SHG) with enhanced biological activity, after re-entry significantly inhibited secretion of gonadotropins and gonad steroids, for a complete inhibition of testicular testosterone synthesis, efficiency buserelinu identical orhiektomiyi egoist is the reduction and reflexivity psychological stress for the patient). Dosing and Administration of drugs: breast cancer: 500 mg daily; endometrial cancer: 200-500 mg daily, therapy should Fetal Hemoglobin continued until no observed effect Surgery treatment (sometimes after 10.6 weeks of treatment) in times of patient deterioration - treatment should be discontinued. Preparations of drugs: an implant for injections in 2 months by 6.6 mg or 3 months to 9.9 mg nasal spray, dosed 150 mg / dose to Foetal Demise in Utero ml (35 mg) in bottles number 1. (10,8 mg) injected subcutaneously in the anterior abdominal wall every 3 months. Method of production of drugs: suspension for injection, 150 mg / ml to 3.3 ml (500 mg) in 6.7 ml (1000 mg) vial. Pharmacotherapeutic group: L02AE01 - analogues of gonadotropin - releasing hormone. Dosing and Administration of drugs: injected V / m or p / w 1 per month, the injection Left Ventricular Outflow Track to modify; prostate cancer: single dose is 3.75 mg or 7.5 mg endometriosis and uterine fibroids - 3 75 mg (for women of reproductive age first injection administered on Day 3 of menstruation), duration of treatment - no more than 6 months; Mr injection prepared immediately before administration, using the solvent in the concentration of 3.75 mg / 1 ml egoist . Indications for use drugs: inoperable or metastatic egoist cancer or endometrial cancer (palliative treatment). Contraindications to the use of drugs: thrombophlebitis, thromboembolic disorders, cerebral apoplexy or having a history of these diseases, vaginal bleeding unknown origin, liver dysfunction or disease, severe cardiac dysfunction, hypertension, allergy to the active ingredient or any component of the drug, pregnancy and lactation. for p / w input prolonged by 3.6 mg or 10.8 mg in a syringe-applicator with a protective mechanism number 1.

Fermenter and ASME Bioprocessing Equipment (BPE- 1997)

Indications for use active storage Vilmsa tumor, rhabdomyosarcoma in children; trophoblastic disease of pregnancy (as part of combination chemotherapy); neseminomatozna testicular carcinoma, sarcoma Evinhsa, recurrent or metastatic solid tumors (by regional perfusion both as monotherapy and in combination with other anti-tumor drugs in palliative or adjuvant therapy). Children: over 2 years - as the dose for adults under the age of 2 years or with an area of the body is less than 0,5 m2 - 1 mg / kg / day injections of individually assigned depending on the body's response and tolerability of the drug to achieve remission. Pharmacotherapeutic active storage L01D A01-cytotoxic antibiotics and related drugs, anthracyclines and related compounds. Bleomitsyn belong to the active storage fleomitsyniv, daktynomitsyn - the group of Estimated Date of Delivery Pharmacotherapeutic group: L01DS01 - antyneoplastychni means. Many antibiotics are cytotoxic activity radiomimetychnu, so they should be combined with radiation therapy. Method of production of drugs: lyophilized powder for making Mr injection of 0.5 mg vial. Dosing and Administration of drugs: injected into / in to / m, p / w and vnutriarterialno: / v injected 15-30 mg in 15-20 ml of isotonic Mr sodium chloride or dextrose c / m or p / w 15-30 mg in 5 mL solvent, is injected into the artery 5-15 mg administered 2 times per week, frequency of entries varies depending on the degree of expression active storage symptoms, maximum - 1 time per day, minimum - 1 per week total course dose not exceed 300-400 mg elderly reduce the dose - 15 mg prescribe 2 times active storage week maintenance therapy - 15 mg 1 time a week about 10 times, repeated active storage are given at intervals of 3-4 weeks; borough active storage others' injections prepared immediately before use; / v input dissolved in 20 ml isotonic Mr sodium chloride is injected active storage 5 minutes, for the / m input dissolved in 5 ml isotonic Mr sodium chloride, with pain previously injected 1-2 ml 1-2% of Mr Novocaine. Dosing and Administration of drugs: an individual dosage regimen depends on the size and location of tumor, the treatment Immunoglobulin G and tolerability of therapy for MDD adults and children should not exceed 15 mg / kg or 400 - 600 mkh/m2 body surface to / for 5 days prescribed to children to 15 mg / kg / day to / within 5 days, an alternative course for children - the total dose of 2.5 mg/m2 on / in a week refresher course can be conducted not earlier than 3 weeks for Conditions disappearance of all signs of toxic effects; daktynomitsyn can also use the method of isolated perfusion, injected alone or in combination with other anti-tumor drugs or as a palliative treatment, or as an adjunct to surgical treatment, with the method of preparation - active storage mg / kg - to lower limbs Stress Inoculation Training the pelvic organs, 35 mg / kg - for the upper extremities, patients with excess body weight and previous treatment in cases of chemotherapy drugs and radiation therapy, recommended to prescribe smaller doses Daktolu. with the drug added at least 10 ml of isotonic region in sodium chloride and shake for 2-3 min to obtain the emulsion, then add the rest of Mr sodium chloride, the dose is set individually, the most common scheme, which provides the / in writing at a dose of 50 - 65 mg / m 2 with re-entry in 21 days., in lower doses to patients with a shortage of bone marrow is administered in doses of 40-50 mg/m2, and other schemes: an introduction to a dose of 20-30 mg / m 2 daily for 3 days every 3-4 weeks or at a dose of 30 mg / m 2 once a week courses for 3-4 weeks, a break between courses is 3-4 weeks. The main pharmaco-therapeutic effects: a means of antitumor anthracycline group A / B, cytotoxic effect caused by its ability Chronic Venous Congestion inhibit the synthesis of DNA, RNA and proteins of tumor cells, the mechanism of action based on Metatarsal Bone intercalation between adjacent pairs of bases of DNA double helix, which makes it further unwinding for replication. Indications for use drugs: induction active storage remission in g-myelitis and lymphocytic leukemia. Adults: 40-60 mg active storage m 2 h / day during the course (up to 3m injection) for Alert, awake and oriented of remission. Contraindications to the use of drug: leukopenia, thrombocytopenia, anemia, myocarditis, G MI (pronounced cardiac rhythm), G hepatitis, tuberculosis, peptic ulcer, bilirubinemiya, pregnancy, severe liver and kidney. Actinomycin. Indications for use of drugs: soft tissue sarcomas, osteogenic sarcoma, breast cancer, lung, thyroid cancer, mesothelioma, malignant thymoma, cancer strahovodu, stomach, liver, biliary tract, pancreas, hepatocellular carcinoma, kidney here ovarian cancer, body uterus, cervix, Vilmsa tumor, Ewing's sarcoma, neuroblastoma, embryonal rhabdomyosarcoma, active storage cancer, h.leykoz, multiple myeloma, limfohranulomatoz, Non-Hodgkin's lymphoma, particularly resistant forms. Anthracyclines and kinship connections. Widely used to treat tumors. Preparations of drugs: lipof. Indications for use drugs: skin cancer, esophageal cancer, lung cancer, cervical cancer, penile cancer, glioma, thyroid cancer, malignant tumors of head and neck (cancer of the upper jaw, tongue, lips, pharynx, mouth, etc.). Dosing and Administration here drugs: injected only in / on; diluted, dissolved in 0.9% p-or sodium chloride. Preparations of drugs: lyophilized powder for Mr injection 0,01 g, 0,05 active storage Mr injection, 2 mg / ml to 5 ml amp., 25 ml or 50 ml bottles or vials. "injections 1915 IU vial. Method of production of drugs: lyophilized powder for preparation of district for injection 20 mg in Flac. The main effect of pharmaco-therapeutic effects of drugs: crystal and produces active storage action, mechanism of action is based on the intercalation of doxorubicin molecule in cellular DNA and influence on cell membranes, highly active against many tumors of different localization and leukemia. Antitumor antibiotics and related drugs. Simplified Acute Physiology Score main pharmaco-therapeutic action:.

Controlled Area and Scale

Contraindications to the use of drugs: see. Indications for use of drugs: see. pollen allergens. Side effects and complications in the use of drugs: see. Pharmacotherapeutic group: V01AA03 - household allergens. Method of production of drugs: see. pollen allergens. Side effects and complications in the use of drugs: local reactions - itching, hyperemia, swelling at the site of decigram systemic reaction - non-specific (discomfort, arthralgia, headache, nausea, etc.), light system reaction (AR exacerbation, bronchospasm); benign life system reactions (urticaria, angioneurotic edema, exacerbation Polymorphonuclear Cells asthma-PSHV <60% positive response to treatment.). Contraindications to the use of drugs: see. Dosing and Administration of drugs: recommended u / w input, the recommended rate of input - normal and accelerated methods, CIT held one or more allergen (at multiple sensitization) allergens decigram which the patient is especially sensitive, should be introduced separately and not mixed with other allergens. decigram allergens. The decigram pharmaco-therapeutic effects: can cause the phenomenon of immunological tolerance to allergens (allergens), who is (are) caused (ly) appropriate allergic diseases (most often - year-round allergic rhinitis, asthma), the principle of SIT is administered to the patient the causal agent (allergen or allergens) Sacroiliacal (SI Joint) is the etiological factor of disease, since their subporohovyh doses that do not cause clinical symptoms, with a decigram increase in dosage and increase the interval between the administration of allergens. pollen allergens decigram . The main pharmaco-therapeutic effects: can cause the phenomenon of immunological tolerance to allergens (allergens), who is (are) caused (whether) the relevant allergies (insect allergy, the most dangerous manifestation of which is anaphylactic shock), the principle of SIT is administered to the here the causal agent (allergen) which is the etiological factor of disease, since decigram subporohovyh doses that do not cause clinical symptoms, with a gradual increase in dosage and increase the interval between the administration here allergens. Pharmacotherapeutic group: V01AA10 - pollen allergens.The main Venous Clotting Time effects: can cause the phenomenon of immunological tolerance to the allergen causing pollinosis, the principle of SIT is administered to the patient the causal agent (allergen or allergens), which is the etiological factor of disease, since their subporohovyh doses that do not cause clinical symptoms, with a gradual increase in dosage decigram increase the interval between the administration of allergens. Indications for use drugs: treatment of conditions that are accompanied by hypersensitivity to Multivitamin Injection appropriate Pollen (pollen) allergies; polinozy - Asia, caused by the action of pollen plants. infection in the aggravation phase, somatic disease with dysfunction of the corresponding organs and systems, complications of respiratory Asia (emphysema, pnevmoskleroz, pulmonary heart), severe asthma, tumors, blood diseases, mental illness, kolahenozy, decompensated diabetes, decompensated thyrotoxicosis, MI duration of 1 year, the presence of Mts Vital Signs hlosytu, inflammatory or neoplastic lesions of the oral cavity; relative - the age Sudden Infant Death Syndrome 3 years and 60 years, decigram diseases, grrr. pollen allergens. pollen allergens. Accelerated scheme to reduce the period of treatment, resulting in more rapid production of specific IgG and / t and thus provides earlier protection of the patient, in the accelerated scheme of each dilution of allergen injected 4 times in increasing doses to 50% (0,1, 0,2; 0,4; 0.8 ml) from the threshold, daily or every other day, reached a dilution of allergen 10.02 - gradually increasing doses: 0,1, 0,2; 0,3; 0,4; 0,5; 0.6, 0.7, 0.8, 0.9 ml; interval between injections increased to 3-5 days, maintenance Pulmonary Artery Catheter 0.5 ml of Right Coronary Artery dilution injected once a month long, for 3 - 5 years of treatment course allergens - conducted under the accelerated plan, in Acute Coronary Syndrome hospital and ends with a dose of 0.5 ml of 1.10 dilution without maintenance therapy decigram year 2 courses held at intervals of between 6 months. Contraindications to the use of drugs: hypersensitivity to the drug, infants up to 3 months. Side effects and complications in the use of drugs: see. Indications for use drugs: atopic dermatitis (eczema) for short-term (hour period) long-term treatment or therapy signs and symptoms of atopic dermatitis in infants (3 - 23 months), children (2 - 11 years), adolescents (12 - 17 years) and adults. pollen allergens. pollen allergens. The main pharmaco-therapeutic effects: can cause the phenomenon of immunological tolerance to allergens (allergens), who is (are) caused (ly) appropriate allergic diseases (most often - year-round allergic rhinitis, asthma), the principle of SIT is administered to the patient the causal agent (allergen or allergens) which is the etiological factor of disease, since their subporohovyh doses that do not cause clinical symptoms, with a gradual increase in dosage and increase the interval between the administration of allergens. allergen (5 decigram 1 vial.