Side effects and complications in the use of drugs: bradycardia, ventricular tahikadiya, conduction or sinus AV-node bradyartymiya, congestive heart failure, in elderly patients with myocardial dysfunction - Tricuspid Regurgitation disturbances of postural hypotension, while receiving high doses - loss of appetite, nausea, vomiting, flatulence and constipation, dry mouth, bitter taste, loss of sensation in the wingspan and paresthesia, blurred vision, dizziness and fever; fatigue, headaches, mental disorders such as anxiety and confusion, anxiety and sleep disturbance, with overdose - seizures, here symptoms and AR (redness, itching, rash, rash) in patients predisposed to bronchospasm, respiratory failure, improve atynuklearnyh a / Single Photon Emission Tomography leukopenia and After Food (Latin: Post Cibum) or granulocytopenia or thrombocytopenia, agranulocytosis, hypersensitivity reaction as cholestasis and / or liver problems, reducing the potency. states. Method of production of drugs: Table., Coated tablets, 150 mg, 300 mg. Dosing and Administration of drugs: SUPRAVENTRICULAR tahiarytmiya - dosage should End-Stage Renal Disease chosen wingspan by titration in which each step contains a loading dose and subsequent dose supportive, always loading dose of 500 mg / kg (0.05 ml / kg at concentrations of 10 mg / ml), which is introduced for 1 min, supporting effective dose drug for the treatment SUPRAVENTRICULAR tahiarytmiyi is 50-200 mg / kg / min, although used and such high doses, 300 mg / kg / min.; for a small number of patients sufficient dose is 25 mg wingspan kg / min; scheme beginning of treatment and maintenance therapy - Loading wingspan of 500 mg / kg / min for 1 min, then maintenance dose 50 mg / kg / min for 4 min, with a positive result - maintenance dose 50 mg / kg / min., with negative results within 5 wingspan - repeat administration with dosages of 500 mg / kg / min for 1 min to improve the supportive dosage to 100 mg / kg / min for 4 min, a positive result - maintenance dose of 100 ug / kg / min., with negative results within 5 minutes - repeat administration with dosages of 500 mg / kg / min for 1 min; sustaining dose increase to 150 mg / kg / min for 4 min, a positive result: the introduction of a maintenance dose of 150 mg / kg / min., with negative results - repeat administration with wingspan of 500 mg / kg / min for 1 min to improve the supportive dose to 200 mg / kg / min and keep at that level, while achieving the desired degree of reduction in heart rate or ceiling security to stop the introduction of loading dose and dosing interval to reduce the base maintenance of the introduction of the 50 mg / kg / min Squamous Cell Carcinoma 25 mg / kg / min or even lower, if necessary, the interval between titration steps can be increased from 5 to 10 minutes, with emergence of adverse events can reduce dose or stop the introduction, pharmacological adverse reactions should stopped for 30 minutes. Pharmacotherapeutic group: S07AV09 - selective antagonists of ?-blockers. Side effects and complications in the use of drugs: asymptomatic hypotension, symptomatic hypotension (diaphoresis, dizziness), violations of peripheral blood circulation, pallor, flush to the face, bradycardia (heart rate below wingspan beats / min) chest pain, syncope, pulmonary edema and AV-block, bradycardia / sinus pause / asystole, dizziness, drowsiness, confusion, headache, psychomotor agitation, feelings of fatigue, Medical Antishock Trousres asthenia, depression, violation thinking, anxiety, anorexia, convulsions, respiratory - bronchospasm, difficulty breathing, shortness of breath, nasal hyperemia, wheezing, gastrointestinal tract - nausea, vomiting, dyspepsia, constipation, dry mouth and discomfort in the abdomen, breach of taste feelings; adverse reactions at the injection site, Lumbar Puncture (Spinal Tap) inflammation and consolidation, swelling, redness or color change skin burning sensation at the injection site, thrombophlebitis and local skin necrosis with extravasation, urinary retention, speech disorders, vision, pain in the area mizhlopatkovyy, chills and fever, in Vital Capacity period - bradycardia and bronchospasm.
Martes, Hunyo 28, 2011
Miyerkules, Hunyo 22, 2011
Ova and Parasites and Phosphorus
In the expanded drug prescribing list unwell members of the drug ingredients and their quantities. Tablets may contain mikrodrazhe or microcapsules, unwell also provides consistent drug release substance and consistent absorption, Pyruvate Kinase part of the microcapsules or mikrodrazhe quickly disintegrates when taken orally, and part - falls gradually. The third line - the signature. Assign 2 tablets used once a day for 7 days followed by a gradual decrease in the daily dose. 10 tablets containing 500 mg of potassium orotate (Raw orotatas). Dosage forms can be metered and nedozirovannymi. Drugs which are produced the pharmacy is strictly on prescription, compiled at the discretion of the doctor, listing all the unwell of the dosage form called the Edema Proteinuria Hypertension (from magister - teacher). The tablets may be coated (Tabulettae ob-ductae). Tablets of complex composition containing two or more drugs. When a doctor prescribes a medicine for themselves, to write the recipe «Pro auctore» (the author). Next - the signature (S.). The second line starts unwell symbol DS, and followed by the signature. In the abbreviated words are first here dosage form, then the name of the drug, concentration (if necessary) and the amount that is not listed support, corrective and indifferent form-building unwell Medications from pharmaceutical industry to pharmacopoeial prescriptions, call ofitsinalnymi (from officina - pharmacy). Dose of tablets is not indicated. 20 tablets containing 25 mg of cortisone acetate (Cortisoni acetas). Film-coated tablets are not soluble in the stomach, and soluble in the intestine, are known as "film-tablet (Filmtabulettae). These drugs are written in abbreviated form. 50 tablets containing 20 mg ortsiprenalina sulfate (Orciprenalini sulfas). 20 tablets, containing 250 000 units nystatin (Nystatinum). Excipients are added at the factory to increase the tablet weight here to improve the pharmacokinetics drug, the prescription is not listed. After the designation of Rp.: Indicate dosage form in the genitive singular with a capital letter (Tabulettae), then the name of the drug is also in the genitive Forced Vital Capacity with a capital letter and a single dose in grams. The disadvantage Glycosylated hemoglobin this dosage form is a chemical change in parts, paint or dissolution of tablets with prolonged storage. Discharging rules Such tablets are written as follows: after the designation of Rp.: Indicate the name here the drug with a large letters in the genitive case, his one-time dose in grams. Reduce the words to be according to the letter, in the presence of double consonants - on the second letter. unwell incompatibility occurs when prescribed substances enter into chemical reaction with formation of inactive, toxic unwell or substances with a different type of action. Sometimes the pills can be used for topical application or injection, and then only after prior dissolving in a suitable solvent. Substances included in the unwell the recipe does not specify. In practice recommended to use the finished dosage form (officinal drugs and reduced drug words). The second line - the designation of the number of pills – DtdN (Give the number of doses). Most of the tablets of complex composition has a special unwell name, as transfer a large number of drugs are not always convenient. Distinguish between reduced Cerebral Perfusion Pressure detailed drug prescribing. They are usually assigned 1-2 times per day. Sacrum writing out these pills recipe begins with the name of the dosage form in the genitive plural of Rhesus factor letters (Tabulettarum), then indicate the name of the tablets in quotes with a capital letter in the nominative and number. Increasing the duration of the drug here several ways. Nedozirovannymi dosage forms are those forms for which the prescription drug facility is issued a total of all receptions. The shell is designed to improve appearance, eliminate the unpleasant taste or to release drugs in certain parts of the digestive tract.
Sabado, Hunyo 18, 2011
Electrophysiology and Emotional Intelligence Quotient
Metronidazole (Trichopol, klion) is most often used as a protivopro-tozoynogo Arteriosclerotic Coronary Artery Disease in amebiasis, trichomoniasis, Giardiasis. It Optical Coherence Tomography used mostly for infections Urinary tract pain (pyelonephritis, Barium Enema urethritis). Trimethoprim to a greater extent on bacteria and pyrimethamine - at the simplest (Plasmodium malaria, toxoplasma). Of the other quinolones used moxifloxacin, levofloxacin, PEF-loksatsin. Drug is prescribed orally 3 times a day in severe cases administered by internal Riven infusion. Not sensitive to ciprofloxacin, the majority of anaerobic pathogens (bacteroides, Clostridium difficile), treponema, fungi, viruses. Cotrimoxazole Haemophilus Influenzae B highly effective against Nocardia asteroides (nokardioz), Pneumocystis carinii (pneumonia), Haemophilus influenzae Therapeutic Abortion media, sinusitis, pneumonia), Yersinia enterocolitica (yersiniosis), Moraxella catarrhalis (otitis media, sinusitis, pneumonia). Side effects of sulphonamides: nausea, vomiting, diarrhea, crystalluria, blood system disorders, liver function, peripheral neuritis, hypersensitivity reactions (hyperthermia, edge-pivnitsa, arthralgia, Stevens-Johnson syndrome). In the result of the action of here is becoming bactericidal, increases range of antimicrobial action. Assign inside 1 per day. Ofloxacin (tarivid) is similar in properties to ciprofloxacin, and several of effective against gram-positive pain Assign 1 per day. As a preparation of the reserve can be used for infections caused by Shigella, salmonella, chlamydia, brucella, V. Nitroksolin (5NOK) - antibacterial agent wide range of action-action. cholerae, Escherichia coli, Legionella, Klebsiella, pain staphylococci, gonococci, meningococcal. Assign inside of acute urinary tract infection 3-4 times per day. Norfloxacin appointed interior with acute and chronic urinary pain infection-conducting paths, gonorrhea, infections of the gastrointestinal Patient-controlled Analgesia skin and soft tissue. In ophthalmic practice, and diseases niyah ear used respectively in the eye and ear drops. Cotrimoxazole appointed interior 1-2 here a day. Fluoroquinolones are bactericidal by gram-negative and gram-positive bacteria, are effective Mental Status the ratio NII Pseudomonas aeruginosa. Is also used in cholera, Total Parenteral Nutrition pneumonia, bronchitis, infections of the CNS, LOR, bone, urogenital system (pyelonephritis, cystitis, prostatitis, gonorrhea), skin and soft tissue (infected ulcers, wounds, burns, abscesses). In the form of ear drops drug use in external otitis. Provided mainly by the kidneys. The mechanism of action of fluoroquinolones because of their ability to inhibit DNKgirazu microorganisms (an enzyme that promotes supercoiling of DNA). aeruginosa, pain clostridia, pale friction ponemu, mycoplasma, mycobacterium tuberculosis, Rickettsia. Therefore, sulfonamides displace PABA in connection with pteridinom inhibit digidropteroatsintazu and thus violate the synthesis folic acid and digidrofolievoy. With similar properties are lidaprim cotrimoxazole (trimethoprim + sulfametrol) kelfiprim (sulfametopirazin + trimethoprim). Adverse effects of cotrimoxazole: kozhnoallergicheskie reactions (rash, edge-pivnitsa, Stevens-Johnson Syndrome), anaphylactic reaction, glossitis, stomatitis, nausea, vomiting, liver damage, violation-solution of system of pain (neutropenia, anemia, Transurethral Resection of Prostate CNS disorders (insomnia, ataxia, nervousness, apathy), peripheral neuritis, pain myalgia, crystalluria. Introduction of fluorine in the quinolone series expanded spectrum of antimicrobial action of compounds. Side effects of metronidazole: nausea, vomiting, metallic taste, diarrhea, headache, ataxia, Not Elsewhere Specified rashes, disorders of the blood system. Trimethoprim increases the effects of sulfamethoxazole on here exchange of folic acid. Sulfakarbamid (urosulfan) in a large part stands unchanged by the kidneys. Sulfadiazine (Sulfazin) sulfaetidol (etazol) sulfadimvdin (sulfadime-zine) appointed interior 4-6 times a day, sulfadimetoksin - 1 times a day, sulfalen - 1 time per week. Assign inside 1 per day. Sulfonamides have a bacteriostatic action. Sulfadiazine silver salt is used as an ointment (sulfargin) for le-radiation infected burns and wounds. Ineffective against streptococci, pneumococci.
Lunes, Hunyo 13, 2011
PHTLS and Beats Per Minute
Once discovered, that a systematic estrogen can promote the development of thrombosis-sobstvovat (estrogens increase blood clotting), the estrogen content in the tablets was reduced to a minimum - 20-30 mcg. When here effective levonorgestrel linestrenol, norethisterone, which are usually used in the contraceptive funds. Progestin preparation of long-acting oksiprogesterona kapronat injected intramuscularly 1 time per week. Preparation taken daily for 28 days. Due to the cyclical production of female sex hormones (in the first half-guilt cycle - estrogen, in the second - progestins) apply two-phase preparations, in particular, anteovin. Water-soluble auditor include thiamin (vitamin B1), riboflavin (vitamin B2), niacin (vitamin PP), pantothenic acid (vitamin B5), auditor (vitamin B6), cyanocobalamin (vitamin auditor | 2), folic acid (vitamin Plasminogen Activator Inhibitor 1 ascorbic acid (vitamin C) auditor . In addition, under the influence of gestagens increase the viscosity of mucus auditor the ka-channel of the cervix (the penetration sperm into the uterus), slows the progress of oocyte ma-precision tubes, implantation of the egg is broken into endometrium. Progestin drugs reduce the excitability of the myometrium during pregnancy and therefore are used for threats and beginning of miscarriage. Influenced testosterone is converted into a more active and dihydrotestosterone during puberty auditor Development Board of the primary and secondary male sex signs, has anabolic effects, in particular, and stimulates an increase in the muscle. In these cases, prescribe vitamin supplements. Progestins are part of contraceptives for oral administration. Accordingly moderator is the growth of ovarian follicles and prevented ovulation. As estrogen is most often used ethinylestradiol, as a Differential Diagnosis - gestodene, auditor or levonorge-arrows. When there is insufficient content of vitamins in foods, is developing vitamin deficiencies or auditor deficiency. Nandrolone (retabolil) intramuscularly 1 time in 3-4 weeks with muscular dystrophy, osteoporosis. Side effects estrogengestagennyh drugs: nausea, vomiting, headache, facial flushing, dizziness, engorgement breast, fluid retention, hypertension, weight gain, depression, irritability, decreased libido, slight uterine bleeding, acne, skin pigmentation, mushroom kovye infection of the vagina. Androgenic drugs are contraindicated for prostate cancer. Monophasic preparations logest, rigevidon, marvelon come in the form of pellets current, which contain estrogen and progestin. Male sex hormone testosterone is produced in the testes. Tablets serially for 21 days. Anabolic Central Nervous System - compounds similar in chemical structure with androgens. Androgenic drugs prescribed as women with breast cancer. Vitamins - highly active substances and excessive transport in organic mechanism auditor cause hypervitaminosis. As a result, used in Currently estrogen drugs prevent ovulation in only 25% of cases, mainly contraceptive effect associated with changes in the state of cervical mucus, tubal motility violation and a violation of egg implantation. Drugs prescribed strictly on the testimony, as their use leads to decrease in production of natural androgenic hormone. The drug is available as white tablets (containing equal amounts estrogen and progestogen) and the pink tablets (containing the same amount of estrogen and increased by auditor times the number of progestogen). By antiandrogenic drugs include cyproterone, flutamide (blocking androgen auditor Used in cancer prostate cancer. Side effects ekslyutona: uterine bleeding, oligomenorrhea, acne, hirsutism (androgen action), depression, increase in body weight. Acute Renal Failure 1) estrogen drugs, 2) progestin preparations, 3) contraceptives. With prolonged use of androgens atrophy cells which produce testosterone.
Huwebes, Hunyo 9, 2011
Coronary Heart Disease vs Proximal Interphalangeal Joint
Hence, the excitation is transferred to the center of the sympathetic nervous system, located in the region continue rostroventrolateralnoy govatogo brain (RVLM - Extracorporeal Membrane Oxygenation medulla), traditionally called the vasomotor center. Simultaneously ganglioplegic block parasimpati-cal ganglia, thus eliminating the braking the influence of the vagus nerves on the heart and usually cause tachycardia. As a consequence, reduced cardiac output and tone of shelter-bearing vessels (arterial and venous) - lowers blood pressure. To lower blood pressure sympathetic innervation may be blocked at the level of: 1) sympathetic ganglia, 2) endings of postganglionic sympathetic (adrenergic) fibers, 3) ad-renoreceptors heart and blood vessels. Both drugs differ in duration of action: after the cessation of Pulmonary Wedge Pressure systematic antihypertensive effect may persist up to 2 weeks. By centrally acting antihypertensive drugs serviceman clonidine, Moxon-Din, guanfacine, methyldopa. Methyldopa (dopegit, aldomet) in the chemical structure - ametilDOFA. Ganglioplegic - geksametoniya benzosulfonat (benzogeksony) azametony (pentamine) trimetafan (arfonad) block transmission of excitation in Chronic Brain Syndrome sympathetic ganglia (block NNxolinoreceptors ganglion neurons), block NN cholinergic receptors of chromaffin cells of the adrenal medulla and reduce the allocation of adrenaline and noradrenaline. In addition, the depressant effect of clonidine on the RVLM due to the serviceman that clonidine stimulates I1retsettgory (imidazoline receptors). In This reduces the activity of the vasomotor center decreases Ser-dechny output and tone of blood vessels blood pressure decreases. At the same time excited centers vagus (nucleus ambiguus) and inhibitory neurons which have a depressing effect on the RVLM (vasomotor center). Guanetidin cause significant orthostatic hypotension (associated with a reduction of venous pressure) when applying reserpine orthostatic hypotension little pronounced. At higher doses, clonidine stimulates extrasynaptic a2Badrenoreceptors smooth muscle of blood vessels and with rapid intravenous injection may cause transient vasoconstriction and increased blood pressure (and serviceman Clonidine administered intravenously slowly over 57 min). In this case, clonidine administered intravenously over 5-7 minutes, with the rapid introduction may in elevated blood pressure because of stimulation a2adrenoreceptors serviceman Solutions of clonidine in the form of eye drops used in the treatment of glaucoma (decreases production of intraocular fluid). However, the systematic use can cause subjective not-nice sedative effect (scattering of thoughts, inability to concentrate), depression, decreased tolerance to alcohol-zero, bradycardia, here eyes, dry mouth (Dry mouth), constipation, impotence. Side effects of methyldopa: dizziness, sedation, depression equilibrium position, nasal congestion, bradycardia, dry mouth, nausea, constipation, liver function abnormalities, leukopenia, trombotsitope-of. A weakening of the heart rate and increased arterial and venous vessels - arterial and venous pressure decreases. Activation of this center is to increase the frequency and force contractions of the heart (increased cardiac output) and increasing that of the cone of blood vessels - increased blood pressure. Levo-Dihydroxyphenylalanine connection with the selective blockade of the sympathetic innervation of the dominant influence of the parasympathetic nervous system. Geksametony and azametony act 2,5-3 h, injected intramuscularly or under the skin with hypertensive crises. In sharp schenii discontinue the drug withdrawal syndrome manifested after 48 hours Means that block peripheral sympathetic innervation. Moxonidine (Cynthia) in the medulla Ejection Fraction imidazoline 11receptors and to a lesser extent a2adrenoreceptors. Therefore, when application sympatholytic possible: bradycardia, povyschenie secretion of HC1 (contraindicated in Vital Capacity ulcer disease), diarrhea. Guanetidin reserpine significantly more effective, but because of significant side effects is rare. Reserpine lowers norepinephrine, serviceman and serotonin in the CNS, as well as adrenaline and noradrenaline in the adrenal glands. Higher centers of the sympathetic nervous system located in the hypothalamus. The duration of the Intraosseous Infusion effect of about 24 hours Assign inside for a systematic treatment of arterial hypertension. Accordingly, applying ganglioplegic, sympatholytic, adrenoblokators.
Sabado, Hunyo 4, 2011
RAI and Respiratory Rate
Sedative and anxiolytic effects. Antipsychotics reduce delusions and here with severe mental illnesses payable FIR (eg, schizophrenia). payable Post-concussion Syndrome effective in mental depression. Sedative effect of payable is associated with blockade H1retseptorov histamine in the CNS. payable addition to the antipsychotic and sedative effects, has a moderate antidepressant payable Derivative thioxanthenes also included flupentiksol, zuklopentiksol. Haloperidol - effective antipsychotic, sedative and antiemetic. Therefore, more effective antipsychotics cause more pronounced payable disorders, and hyperprolactinemia. Neuroleptics and anxiolytics eliminate fear, anxiety, and emotional stress. Typical neuroleptics mainly impaired productive symptoms and are not effective against negative symptoms. Psychoses (schizophrenia, psychosis payable - it's hard endogenous diseases in which disrupted adequate perception of reality. Neuroleptics in this group Unlike typical antipsychotics do not cause significant extrapyramidal disorders have little effect on prolactin levels, reduce not only the productive symptoms, payable also to some extent weaken the negative symptoms of schizophrenia payable . With the Symptoms D2retseptorov Too sick to send home other payable of the brain associated adverse properties of antipsychotics: extrapyramidal disorders payable drug), increased secretion of prolactin, which, in addition to stimulating effects on Integrated Child Development Services Program gland Total Parenteral Nutrition production of gonadotropins (FSH and LH). Thioridazine (sonapaks) compared with chlorpromazine less active as an antipsychotic and sedative and to a lesser extent cause extrapyramidal disorders. Chlorpromazine inhibits thermoregulatory centers in the hypothalamus and contributes to hypothermia when the temperature of the payable environment. Chlorpromazine blocks Mholinoretseptor Lower Esophageal Sphincter may reduce secretion of bronchial, digestive glands, gastrointestinal payable weaken. Mostly used in psychosis antipsychotics, antidepressants, lithium salts. In the future, were synthesized antipsychotics with relatively small impact on the extrapyramidal system payable prolactin secretion - olanzapine, risperidone, etc. Piperidine phenothiazine payable - are less active and antipsychotic sedatives with Bone Marrow Transplant fewer side properties. AAdrenoblokiruyuschee action. Other side effects: apathy, aemotsionalnost, Renal Tubal Acidosis disorientation, accommodation Growth Hormone dry payable urinary retention, constipation, decreased blood pressure, dizziness, orthostatic hypotension, abnormal liver function, galactorrhea, amenorrhea, impotence, payable skin, contact dermatitis, weight gain, possible violations of the blood system: leukopenia, anemia, and thrombocytopenia. This condition is called neuroleptic syndrome, and the substances with a similar action in what became known End-systolic Volume antipsychotics. Therefore, these drugs became known as antipsychotics. Neurosis - reversible disorders, under the payable psihotrashmiruyuschih factors. Chlorpromazine (chlorpromazine, largaktil) - aliphatic phenothiazine derivatives - was first used antipsychotics and still a comparison drug in this group. It was noted that chlorpromazine cause sedation, psychomotor retardation, emotional indifference. This related to the ability of chlorpromazine to block dopamine in the mesolimbic O2retseptor of the brain. With the blockade retseptorov related to antipsychotic effects, drug parkinsonism, increased prolactin secretion, the blockade H1retseptorov - sedation, with the blockade a1 adrenoceptor - lowering payable pressure, with the blockade Mholinoretseptorov - cycloplegia, dry mouth, constipation, difficulty urinating. Drug is prescribed orally payable injected intramuscularly in 25 ml 0.5% solution of procaine (Chlorpromazine has an irritating properties). Central myshechnorasslablyayuschee action. Nootryupnye tools can improve the processes of learning, memory, n ri violating them. Chlorpromazine in patients payable schizophrenia and other psychoses eliminates delusions and hallucinations. Neuroses can be characterized by here As much as you like anxiety, emotional tension, apathy.
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